Studio / Explainer
Explainer · simulated data
From β to M, at a glance
M = log2(β / (1 − β))
dM/dβ = 1 / (ln 2 · β(1 − β))
1,500 CpGs · 8 replicates
Transform
0% transformed
ABeta scaleTrue methylation levels on the bounded 0–1 scale
BETA SCALE 00%
Two crowded peaks near the walls.
BTransform curveDrag sideways to slide the Δβ window · click a dot to pin it
CReplicate noise vs meanSD of 8 replicates against their mean · morphs with A
Every number on this page is simulated in your browser from a mixture of beta distributions; no study data is used. The β-to-M transform is the one used for 450K/EPIC methylation arrays.